The primary active components found in bitter orange are adrenergic amines, including synephrine. Synephrine is similar to ephedrine and acts as a natural stimulant. Studies show that Advantra Z increases resting metabolic rate and promotes the breakdown of fat. These effects are achieved by stimulating the beta-3 cell receptors which help the body’s response to adrenergic amines such as adrenalin and noradrenalin.
The beauty of Advantra Z is that this is achieved with minimal impact on other receptors which are responsible for increased heart rate and heightened blood pressure. Because many stimulants can have been associated with negative impacts on health, it’s important to note multiple safety studies have been conducted on Advantra Z. There are now more than 20 studies evaluating the safety of Advantra Z. In fact, the FDA released a report last year attesting to the safety of Advantra Z specifically.
The numerous studies make this ingredient one of the most patented thermogenic ingredients with effects and safety in the weight management, sports nutrition and energy categories. For a more detailed view of the scientific research, please click here.